Coffee Lovers Sensitive to Caffeine's Bitter Taste: StudyHealthy Living

November 17, 2018 17:30
Coffee Lovers Sensitive to Caffeine's Bitter Taste: Study

(Image source from: Deccan Chronicle)

People who are more sensitive to coffee's bitter taste indeed drink more of the brew, a study suggests.

The study which is published in the journal Scientific Reports found that the sensitivity is caused by a genetic variant.

"You'd expect that people who are particularly sensitive to the bitter taste of caffeine would drink less coffee," said Marilyn Cornelis, assistant professor at Northwestern University in the United States.

"The opposite results of our study suggest coffee consumers acquire a taste or an ability to detect caffeine due to the learned positive reinforcement (ie stimulation) elicited by caffeine," Cornelis said.

"People who have a heightened ability to taste coffee's bitterness - and particularly the distinct bitter flavor of caffeine - learn to associate good things with it," she said.

In the study group, people who were more sensitive to caffeine and were consuming a lot of coffee consumed low amounts of tea.

The study also found people sensitive to the bitter flavors of quinine and of PROP, a synthetic taste accompanying the compounds in cruciferous vegetables, avoided coffee.

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For alcohol, a higher sensitivity to the bitterness of PROP ensued in lower alcohol consumption, particularly of red wine.

"The findings suggest our perception of bitter tastes, informed by our genetics, contributes to the preference for coffee, tea, and alcohol," Cornelis said.

Scientists applied Mendelian randomization, a technique very often used in disease epidemiology, to trial the causal relationship between bitter taste and beverage consumption in over 400,000 men and women in the United Kingdom.

The genetic variants linked to caffeine, quinine, and PROP perception were previously identified through genome-wide analysis of solution taste-ratings collected from Australian twins.

These genetic variants were then tested for associations with self-reported intake of tea, coffee, and alcohol in the current study.

"Taste has been studied for a long time, but we don't know the full mechanics of it," Cornelis said.

-Sowmya Sangam

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coffee  caffeine  tea