Flavoured E-Cigarette Possibly More Toxic than Regular Cigar: StudyOctober 13, 2018 15:44
(Image source from: Mirror)
Seasoning and supplement ingredients in e-cigarettes may rise inflammation and damage lung function, according to a study.
The research, published in the American Journal of Physiology-Lung Cellular and Molecular Physiology, as well found that short-term vulnerability to e-cigarettes was adequate to cause lung inflammation similar or worse than that seen in handed-down cigarette use.
E-cigarettes, popular battery-powered devices that imitate the act of smoking a traditional cigarette, dispense a vapor derived from liquid chemicals in a refillable cartridge.
The refills in most cases contain propylene glycol, nicotine and often flavorings, said researchers from the University of Athens Medical School in Greece.
Propylene glycol - an odorless, colorless, food additive - is found in numerous processed food and liquid refreshments; it is likewise utilized as a solvent in a number pharmaceutical.
E-cigarette devices and refills are not well regulated, and the long-term health effects of e-cigarette use are not widely known.
Several groups of mice were studied by researchers that received whole-body exposure to varying chemical combinations four times daily. Each exposure session was separated by 30-minute smoke-free intervals.
The e-cigarette and cigarette groups were compared with a control group that was open to medical-grade air.
Some of the animals in each group were exposed to short-term cigarette smoke or e-cigarette vapor (three days), while else were exposed for a longer term (four weeks).
The team found a growth in markers of mucus production inflammation and changed lung function in the propylene + nicotine, propylene, and flavoring groups after three days.
However, the propylene group showed fewer negative effects with long-term exposure, suggesting the additive alone elicits only a temporary irritation that eventually subsides with continued use.
Additionally, two inflammation-producing proteins became elevated solely in the flavoring group, proposing that some of the many flavoring components on the market may not be harmless for even short-term use.
When the condition of the e-cigarette groups compared to the cigarette group, the level of oxidative stress - stress at a cellular level - in the flavoring group was equivalent to or higher than that of the cigarette group.
However, respiratory mechanics were adversely affected solely in mice exposed to cigarette smoke and not to e-cigarette vapor after drawn-out treatment.
"The observed detrimental effects in the lung upon (e-cigarette) vapor exposure in animal models highlight the need for further investigation of safety and toxicity of these rapidly expanding devices worldwide," the researchers said.